在整个生命过程中与手握强度相关的因素:系统性审查
Leticia W Ribeiro1, Sara Berndt1, Gregore I Mielke1
1School of Public Health, The University of Queensland, Brisbane, Queensland, Australia.
Journal of cachexia, sarcopenia and muscle
|August 26, 2024
概括
肌肉强度,以手握强度 (HGS) 衡量,随着年龄和男性性别而下降. 炎症和心血管疾病等可修改因素显著影响HGS,突出了健康衰老干预措施的目标.
科学领域:
- 老年学和运动科学
- 公共卫生和流行病学
背景情况:
- 肌肉强度,特别是手握强度 (HGS),是健康衰老和整体健康的关键指标.
- 之前的研究发现了与HGS相关的横截面因素,但纵向预测因素仍未得到充分研究.
研究的目的:
- 系统地审查和综合有关随着时间的推移与成人手握强度 (HGS) 相关的因素的证据.
- 在随访时确定HGS的决定因素及其在整个生命过程中的变化速度.
主要方法:
- 在 MEDLINE,Embase 和 SPORTDiscus 数据库中进行了系统的文献搜索.
- 包括纵向研究,研究了影响成年HGS随时间推移的因素.
- 利用基于显示与HGS一致关联的研究比例的半定量分析.
主要成果:
- 117篇文章确定了103个与HGS相关的潜在因素,其中10个显示出一致的纵向关联.
- 增加年龄,男性性别,炎症标志物升高和心血管疾病与更大的HGS下降有关.
- 较高的出生体重与较强的HGS相关,而抑郁症状与较弱的HGS相关.
结论:
- 虽然年龄和性别是HGS下降的主要驱动因素,但炎症和心血管健康等可改变的因素是关键的干预目标.
- 改善出生体重和心理健康可能会对肌肉力量轨迹产生积极影响.
- 需要进一步的研究,以充分阐明HGS的复杂决定因素,以便有效的卫生干预措施.
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