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Updated: Jun 15, 2025

A TNBS-Induced Rodent Model to Study the Pathogenic Role of Mechanical Stress in Crohn's Disease
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通过循环中介抑制核动素聚合的加剧性性结肠炎

William W Du1,2, Chi Zhou1,2,3,4,5, Hui Yang6

  • 1Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.

Research (Washington, D.C.)
|August 26, 2024
PubMed
概括

循环RNA circNlgn通过产生Nlgn173蛋白质促进结肠炎,该蛋白质破坏结肠上皮细胞中的actin聚合. 抑制cirNlgn或Nlgn173可能为性结肠炎提供新的治疗方法.

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