职业暴露对慢性鼻炎的影响:一个范围审查
Aurelia S Monk1, Cameron P Worden1, Ezer H Benaim1
1Department of Otolaryngology and Head & Neck Surgery, University of North Carolina, Chapel Hill, NC, 27599, USA.
概括
职业暴露与慢性鼻炎 (CRS),一种常见的鼻炎症有关. 需要使用标准化方法进行更多的研究来证实这种联系,并为这种广泛的疾病制定预防策略.
科学领域:
- 环境健康 环境健康
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 流行病学 流行病学
背景情况:
- 慢性鼻炎 (CRS) 是一种广泛的,使人衰弱的疾病,影响鼻.
- 预防CRS至关重要,职业暴露是干预的潜在目标.
- 虽然职业暴露与下呼吸道疾病有关,但它们在CRS等上呼吸道疾病中的作用不明.
研究的目的:
- 检查职业暴露与慢性鼻炎 (CRS) 的发展之间的关联.
- 审查关于CRS职业风险因素的现有文献.
主要方法:
- 根据系统性审查和元分析 (PRISMA) 准则的首选报告项目进行了范围审查.
- 确定并分析了19项相关研究.
- 研究方法,CRS诊断标准和职业暴露评估差异很大.
主要成果:
- 在审查的研究中观察到职业暴露和CRS诊断之间的一般关联.
- 在研究设计,CRS的诊断标准和职业暴露评估方面注意到了显著的异质性.
- 方法上的局限性阻碍了关于特定职业暴露和CRS的最终结论.
结论:
- 实质性证据表明,职业暴露与慢性鼻炎 (CRS) 之间存在联系.
- 研究中的方法不一致性需要使用标准化标准进行更严格的研究.
- 未来的研究需要大量,多样化的群体,共识的CRS诊断标准,以及具体的定量暴露评估,以告知预防策略.
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