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Updated: Jun 15, 2025

Potentiation of Anticancer Antibody Efficacy by Antineoplastic Drugs: Detection of Antibody-drug Synergism Using the Combination Index Equation
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双重TTK/PLK1抑制在TNBC中具有强大的抗癌活性,作为单一治疗和组合治疗

Elisa Zanini1, Nicole Forster-Gross1, Felix Bachmann1

  • 1Basilea Pharmaceutica International Ltd, Allschwil, Switzerland.

Frontiers in oncology
|August 26, 2024
PubMed
概括

一种新型的氨酸氨酸激酶 (TTK) 和波罗类激酶1 (PLK1) 的双重抑制剂,BAL0891,在临床前模型中显示出强大的抗癌活性,包括三阴性乳腺癌 (TNBC). 这种双重抑制策略为癌症治疗提供了一个有希望的新途径.

关键词:
BAL0891 一个问题在Mps-1中,Mps-1是指MPS-1的值.PLK1 PLK1 的意思是这就是SAC SAC.TTK TTK 在这里.线性检查点抑制剂 线性检查点抑制剂

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