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Updated: Jun 15, 2025

Optimization of a Multiplex RNA-based Expression Assay Using Breast Cancer Archival Material
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Optimization of a Multiplex RNA-based Expression Assay Using Breast Cancer Archival Material

Published on: August 1, 2018

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免疫透与原发性ER+侵袭性叶状乳腺癌中的转录组亚型相关

Fangyuan Chen, Sayali Onkar, Jian Zou

    Research square
    |August 26, 2024
    PubMed
    概括

    这项研究揭示了两种乳腺癌亚型和ER+/HER2-侵袭性叶状癌的免疫模式. 一个增殖亚型显示了更多的免疫抑制细胞,而一个TAM-Low签名预测了更好的结果.

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    Evaluation of Tumor-infiltrating Leukocyte Subsets in a Subcutaneous Tumor Model07:49

    Evaluation of Tumor-infiltrating Leukocyte Subsets in a Subcutaneous Tumor Model

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    lncRNA - Long Non-coding RNAs

    In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA...
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