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医学图像:B细胞急性淋巴细胞白血病患者的细胞巨乳病毒状腺炎

Javier A Baena-Del Valle¹, Sergio D Cruz-Romero¹, Martha L Romero-Prieto¹

¹Department of Pathology, University Hospital Fundación Santa Fe de Bogotá, Crr. 7 # 117-15, Bogotá, Colombia.

|August 26, 2024

概括

细胞巨乳病毒 (CMV) 可以在免疫功能低下的人中引起严重的疾病. 这一案例突显了白血病患者的罕见唾液腺感染CMV sialadenitis,强调了迅速诊断的必要性.

科学领域:

传染性疾病传染性疾病
在瘤学瘤学.
免疫学免疫学免疫学

背景情况:

细胞巨乳病毒 (CMV) 感染是常见的,但在儿童时期通常无症状,建立终身潜伏.
免疫受损宿主中的重新激活可以导致严重的多器官疾病,尽管唾液腺参与不常见.
接受化疗的血液恶性瘤患者有机会性感染的高风险.

研究的目的:

在免疫功能低下的患者中报告一种罕见的细胞巨乳病毒腺炎 (唾液腺感染) 病例.
强调在免疫受损个体腺胀的差异诊断中考虑CMV的重要性.

主要方法:

一个66岁的B细胞急性淋巴细胞白血病患者接受移植前治疗的病例研究.
临床表现包括右耳前耳道胀和疼痛.
诊断工作包括CT扫描和腺活检与CMV的免疫组织化学.

主要成果:

CT显示右侧腺扩大,高密度和增强,并有胀.
腺活检表明,淋巴细胞透与牛体和含有阳性CMV.
这名患者被诊断出患有CMV sialadenitis.

结论:

冠状病毒腺炎是一种罕见的,但在免疫功能低下的患者中可能出现的并发症,即使是那些处于缓解状态的人.
早期考虑和诊断CMV感染对于免疫功能低下的人群的有效管理至关重要.
这一案例凸显了诊断方面的挑战,以及考虑瘤患者的机会性感染的重要性.

关键词:

细胞巨乳病毒病毒.前体B细胞淋巴细胞白血病-淋巴瘤的前体腺体炎是什么意思

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