诺玛伪装成状细胞癌 - - 一个艾滋病患者的病例报告
R Mahesh Kumar1, T R Marimallappa1, M S Sreelakshmi1
1Department of Oral and Maxillofacial Surgery, Sri Siddhartha Dental College and Hospital, Sri Siddhartha Academy of Higher Education, Tumakuru, Karnataka, India.
Annals of maxillofacial surgery
|August 26, 2024
概括
(Cancrum oris) 是一种罕见的口腔感染. 这一案例凸显了在免疫功能低下的患者中诊断 noma 的挑战,强调了机会性感染.
科学领域:
- 口腔病理学 口腔病理学
- 传染性疾病 传染性疾病
- 免疫性受损的宿主
背景情况:
- (Cancrum oris,noma) 是一种罕见的,激烈的性口腔感染,通常影响营养不良的儿童.
- 这个病例在一个54岁的人类免疫缺陷病毒 (HIV) 阳性男性中提出了诊断挑战,该男性患有模仿状细胞癌 (SCC) 的口腔.
研究的目的:
- 描述临床表现,诊断困难,以及在成年艾滋病毒阳性患者中对cancrum oris的管理.
- 强调考虑口腔病变的免疫功能低下个体的机会性感染的重要性.
主要方法:
- 一个54岁的人类免疫缺陷病毒阳性男性的病例报告.
- 临床检查,组织病理学和免疫组织化学被用于诊断.
- 治疗涉及由于CD4细胞计数减少而开始抗逆转录病毒疗法.
主要成果:
- 该患者出现了严重的口腔,模仿状细胞癌 (SCC).
- 组织病理学最初是误导性的,表明早期的SCC入侵.
- 免疫组织化学结果没有支持SCC诊断.
- 在开始抗逆转录病毒治疗后,病变显示出愈合的迹象.
结论:
- 在免疫功能低下的成年人中诊断cancrum oris存在独特的挑战.
- 在HIV阳性患者口腔的差异诊断中,应考虑机会性感染.
- 及时诊断和适当的治疗,包括抗逆转录病毒疗法,对于管理这种情况至关重要.
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