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患有 TET2 突变的耐火性外周T细胞淋巴瘤的患者对阿扎西提丁的反应
Minh-Anh Le1, Feras Al-Moussally1, Allison Carilli2
1Internal Medicine, University of Central Florida (UCF)HCA Florida Healthcare (Greater Orlando) Internal Medicine Residency Program, Orlando, USA.
Cureus
|August 26, 2024
概括
周围T细胞淋巴瘤 (PTCL) 是具有侵略性的. 一名患有PTCL-NOS的患者,不耐多次治疗,因TET2突变而受到阿扎西蒂丁的引导,反应良好,这表明表观遗传疗法的潜力.
科学领域:
- 血液学 血液学 血液学
- 在瘤学瘤学.
- 分子生物学分子生物学
背景情况:
- 周围T细胞淋巴瘤 (PTCL) 是一种具有高复发率的侵袭性非霍奇金淋巴瘤.
- 没有另有说明的PTCL (PTCL-NOS) 是最常见和最具挑战性的亚型.
- 准确的诊断依赖于集成的分子,组织病理学和免疫类型分析.
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