静脉输入与手套内化的利多卡因用于预防术后喉痛:一项前性随机对照试验
Salma Ketata1, Yassine Maktouf1, Imen Zouche1
1Department of Anesthesiology, Habib Bourguiba University Hospital, Sfax, Tunisia.
The Pan African medical journal
|August 26, 2024
概括
静脉和内利多卡因可显著减少术后喉疼痛和内内输管后的咳. 与安慰剂相比,这两种方法都改善了患者的舒适度.
科学领域:
- 麻醉学 麻醉学
- 临床药理学 临床药理学
- 患者安全 患者安全
背景情况:
- 手术后喉痛 (POST) 是全身麻醉后的常见并发症.
- 气管粘膜损伤是POST的主要原因.
- 对于POST,存在各种预防策略.
研究的目的:
- 为了比较静脉注射和内利多卡因与安慰剂在预防POST方面的疗效.
- 评估这些干预措施对其他术后并发症的影响.
主要方法:
- 进行了一项前性,双盲,随机对照试验.
- 90名接受口腔管道输管计划手术的患者被分为三个组:化的手套内利多卡因,静脉注射利多卡因和安慰剂.
- 结果包括POST发生率和严重程度 (VAS),咳,听力障碍,消化障碍以及手术后24小时内恶心/吐.
主要成果:
- 与安慰剂 (67%) 相比,24小时后POST发生率在静脉注射利多卡因组 (13%) 和手套内利多卡因组 (37%) 中显著较低.
- 这两种利多卡因干预措施在24小时内显著降低了视觉模拟尺度 (VAS) 疼痛评分.
- 与安慰剂相比,化的内利多卡因在减少出现的咳方面表现出优越性 (p=0.02) 并减少了其他不良事件.
结论:
- 静脉注射和手套内利多卡因在口腔输管输管后治疗术后喉疼痛方面都有效.
- 化的手内利多卡因在减少咳方面表现出特别的益处.
- 利多卡因的使用在术后期改善了患者的治疗结果和舒适度.
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