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Updated: Jun 30, 2026

Ex vivo Culturing of Whole, Developing Drosophila Brains
08:39

Ex vivo Culturing of Whole, Developing Drosophila Brains

Published on: July 27, 2012

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非典型的可溶性瓜尼利基循环酶控制Drosophila中的大脑大小

Daniel Prieto1,2, Boris Egger3, Rafael Cantera1

  • 1Departamento de Biología del Neurodesarrollo, Instituto de Investigaciones Biológicas Clemente Estable, Montevideo, Uruguay.

microPublication biology
|August 26, 2024
PubMed
概括

这项研究揭示了Drosophila大脑发育中的一种新的氧气感应途径,与HIF途径不同. 它将cGMP信号与神经干细胞增殖和视叶生长联系在一起.

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Mass Histology to Quantify Neurodegeneration in Drosophila06:34

Mass Histology to Quantify Neurodegeneration in Drosophila

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Monitoring Cell-to-cell Transmission of Prion-like Protein Aggregates in Drosophila Melanogaster10:26

Monitoring Cell-to-cell Transmission of Prion-like Protein Aggregates in Drosophila Melanogaster

Published on: March 12, 2018

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相关概念视频

GPCRs Regulate Adenylyl Cylase Activity01:09

GPCRs Regulate Adenylyl Cylase Activity

Some GPCRs transmit signals through adenylyl cyclase (AC), a transmembrane enzyme. AC helps synthesize second messenger cyclic adenosine monophosphate (cAMP). AC catalyzes cyclization reaction and converts ATP to cAMP by releasing a pyrophosphate. The pyrophosphate is further hydrolyzed to phosphate by the enzyme pyrophosphatase, which drives cAMP synthesis to completion. However, cAMP is rapidly degraded to 5′ AMP by the enzymes phosphodiesterase (PDE), preventing overstimulation of cells.
Two...