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从单核RNA-seq数据进行基失衡分析的实验和计算方法

Sean K Simmons1,2,3, Xian Adiconis1,2,3, Nathan Haywood1,2,3

  • 1Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.

bioRxiv : the preprint server for biology
|August 26, 2024
PubMed
概括

单核RNA测序 (snRNA-seq) 通过利用内部读数来增强基因特异表达 (ASE) 分析. 这种方法在识别与疾病相关的遗传变异方面提供了比eQTL分析更大的力量.

关键词:
帕金森病是帕金森氏症的一种疾病.在RNA-seqqq.单细胞机是一种单细胞机.一个等位基因的特定表达.变种的功能变种的功能.

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相关概念视频

RNA-seq03:21

RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while...
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