内腔支臂治疗程序后的疼痛管理:一个前性,随机化,双盲研究
Jagdeep Sharma1, Harsimran Walia2, Lalita G Mitra1
1Anaesthesia, Critical Care, and Pain Medicine, Homi Bhabha Cancer Hospital and Research Centre, New Chandigarh, IND.
Cureus
|August 26, 2024
概括
与芬太尼相比,内支臂疗法患者经历了与内德克斯梅德托米丁相比的长时间脊髓疼痛缓解. 德克斯梅德托米丁是一种安全有效的选择,用于日常治疗,为患者提供更好的满意度.
科学领域:
- 麻醉学 麻醉学
- 在瘤学瘤学.
背景情况:
- 在胸腔疗法中使用的内腔应用器会在手术后引起显著的不适.
- 人们越来越需要阿片类药物节约麻醉和止痛替代品.
- 适当的骨盆肌肉放松和术后疼痛管理对于手臂治疗患者至关重要.
研究的目的:
- 为了评估 intrathecal dexmedetomidine (3μg) 的日常病例安全性和止痛效果,作为低剂量高压布皮瓦卡因的辅助剂.
- 在接受支臂治疗的患者中,将德克斯梅德托米丁与内芬太尼 (15微克) 进行比较.
- 评估结果,包括医院出院时间,脊柱疼痛缓解的持续时间,疼痛评分,患者满意度和不良事件.
主要方法:
- 预定接受手臂治疗的70名女性患者被随机分为两组.
- 第一个组接受了低剂量的0.5%高压布皮瓦卡因与3μg德克斯梅德托米丁.
- 第二组接受了低剂量的0.5%高压布皮瓦卡因与15μg芬太尼.
主要成果:
- 德克斯梅托米丁组 (I组) 的所有患者在同一天出院,没有任何不良反应.
- 脊柱疼痛缓解的平均持续时间在I组 (406.82分钟) 与II组 (267分钟) 相比显著更长 (p<.001).
- 在I组的患者中,需要救援止痛的患者较少 (在II组为8人,而在II组为17人,p<0.025).
结论:
- 甲状腺内用德克斯梅德托米丁 (3微克) 是白天病例支臂治疗的安全有效辅助剂.
- 与芬太尼相比,德克斯梅德托米丁提供了长时间的脊髓止痛,并提高了患者的满意度.
- 这种方法支持治疗疼痛管理中的阿片类药物节约策略.
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