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Updated: Jun 15, 2025

Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
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在质子化螺旋环4H-pyrazoles之间服1,5-sigmatropic转移

Brian J Levandowski1, Brian J Graham1, Nile S Abularrage1

  • 1Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States.

Journal of physical organic chemistry
|August 26, 2024
PubMed
概括

研究人员探索了合成螺旋环4H-Pyrazoles的方法. 修改pyrazole中间体上的替代剂显著减缓了一个关键反应,使得用于点击化学应用的新型化合物的分离成为可能.

关键词:
4H - 皮拉醇的使用情况密度函数理论密度函数理论一个环周反应反应.西格马热带变化转移.螺旋结合的螺旋结合方式

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