病例报告:儿童,由侵袭性A型菌引起
Danchun Guo1, Shuting Zhuang1, Qinghua Lu1
1Shenzhen Children's Hospital, Shantou University Medical College, Shenzhen, Guangdong, China.
Frontiers in medicine
|August 26, 2024
概括
侵袭性A型链球菌 (iGAS) 软组织在儿童中很罕见. 及时排水和适当的抗生素,如β-乳糖胺,对于有效的治疗和恢复至关重要.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 微生物学 微生物学
背景情况:
- 侵袭性A型链球菌 (iGAS) 感染是儿童死亡的重要原因,尤其是链球菌毒性休克综合征.
- 软组织感染很常见,但由于iGAS而形成疹相对罕见,特别是在儿科患者中.
研究的目的:
- 研究由iGAS感染引起的软组织的儿科患者的临床特征,治疗方法和结果.
- 突出早期诊断的重要性和这些罕见的IGAS表现的适当治疗策略.
主要方法:
- 2016-2018年间从无菌部位诊断出iGAS感染的儿科住院患者的回顾性研究.
- 纳入标准:通过从无菌部位的培养证实iGAS感染的患者,表现为软组织感染和.
- 收集的数据包括患者人口统计,临床表现,实验室发现,治疗和随访结果.
主要成果:
- 14名儿科患者 (10名男孩,4名女孩;年龄3个月10岁) 被确诊患有IGAS软组织,最常见的是下肢.
- 常见的症状包括发烧,局部炎症迹象,白细胞计数升高 (12/14),C反应蛋白 (7/14),以及红细胞沉积率 (10/14). 预色素水平没有升高.
- 所有患者都接受了液排水和抗生素治疗 (主要是β-乳酸药);结果稳定,在2个月的随访期间没有观察到器官损伤.
结论:
- 儿科iGAS软组织需要早期诊断,及时切割和排水,以及排水液的微生物培养.
- β-乳酸抗生素是确认iGAS感染的建议第一线治疗方法;对于耐火病例,可以考虑使用万科米辛.
- 有效的管理导致患者的病情稳定,并防止严重的并发症,如脏或心脏损伤.
相关概念视频
01:30Tonsillitis I: Introduction
216
Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.
Etiology
Three primary contributing factors have been identified.
216
01:23Skin Diseases and Disorders
3.7K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
3.7K
01:30Acute Pharyngitis
504
Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
504
01:26Tonsillitis II: Management
105
This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
105
01:26Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
4.1K
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
4.1K
01:30Pneumonia III: Complications and Assessment
191
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
191