机械通风创伤患者初始CT成像中的身体组成参数:单中心观察性研究
Hans-Jonas Meyer1, Tihomir Dermendzhiev1, Michael Hetz2
1Department of Diagnostic and Interventional Radiology, University Hospital Leipzig, Leipzig, Germany.
Journal of cachexia, sarcopenia and muscle
|August 26, 2024
概括
肌肉质量的丧失,即肉症,是严重受伤的创伤患者30天死亡率的重要预测因素. 这种身体组成参数没有影响重症监护室停留时间或机械通风时间.
科学领域:
- 创伤外科 手术 创伤外科
- 关键护理医学 关键护理医学
- 放射学 放射学是一门学科.
- 身体组成分析 身体成分分析
背景情况:
- 身体组成参数在重症监护和癌症中具有预后价值.
- 之前对多创伤患者的研究给出了关于身体组成的不确定的结果.
- 这项研究旨在调查严重受伤的创伤患者体质组成的预后作用.
研究的目的:
- 分析身体组成参数在严重受伤的创伤患者预测结果中的作用.
- 为了确定身体成分指标是否预测30天死亡率,ICU停留时间和机械通风持续时间.
- 在创伤患者中评估萨尔科佩尼亚,内脏肥胖和萨尔科佩尼肥胖的预后意义.
主要方法:
- 对472名需要机械呼吸的创伤患者进行了回顾性分析.
- 利用从全身创伤CT扫描中获得的计算机断层扫描 (CT) 衍生体质参数.
- 评估了30天死亡率,ICU停留时间和机械通风持续时间的预后变量.
主要成果:
- 标出了萨科佩尼亚作为30天死亡率的一个显著的独立预后因素 (HR 2.84,P=0.004).
- 在49%的患者中存在内脏肥胖,在16%的患者中存在皮症,在7.4%的患者中存在皮性肥胖.
- 在幸存者中,身体组成参数和ICU停留时间或机械通风持续时间之间没有发现显著的关联.
结论:
- CT定义的肉类显著与机械通风创伤患者30天死亡率的增加有关.
- 身体构成参数,包括肉症,与ICU停留时间或机械通风持续时间没有显著关联.
- 萨科佩尼亚在严重创伤患者群体中成为关键的预后指标.
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