阶段解析功能性肺部MRI用于肺透气和输液 (V / Q) 评估
Andreas Voskrebenzev1, Filip Klimeš2, Frank Wacker2
1Institute for Diagnostic and Interventional Radiology, Hannover Medical School; Member of the German Center for Lung Research, Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH); voskrebenzev.andreas@mh-hannover.de.
Journal of visualized experiments : JoVE
|August 26, 2024
概括
阶段解析功能性肺成像 (PREFUL) 是一种新的MRI技术,用于评估没有对比剂的肺通风和 perfusion. 这种经过验证的方法可以进行定量V/Q成像,用于在各种肺部疾病中检测疾病和监测治疗.
科学领域:
- 医疗成像医学成像
- 肺部医学 肺部医学
- 磁共振成像是一种磁共振成像技术.
背景情况:
- 里埃分解是一种无对比剂的1HMRI方法,用于肺部评估.
- 现有的方法需要对比剂或专门的硬件.
研究的目的:
- 引入和验证阶段解析功能性肺成像 (PREFUL) 用于定量通风 (V) 和 perfusion (Q) 评估.
- 为了证明PREFUL在不同领域的优势和患者群体的可行性.
主要方法:
- 使用标准的2D破坏式梯度回声序列,时间分辨率为300毫秒.
- 开发了一种图像排序算法,用于voxel时间序列的相位解析分析.
- 对129Xe/19F气体成像,SPECT和DCE-MRI进行验证的PREEFUL.
主要成果:
- PREFUL 能够为区域流量循环和脉冲波传播提供高时间分辨率成像.
- 与已建立的V/Q成像技术有很好的区域一致性.
- 在各种场强度 (0.55T-3T) 和年龄组 (包括新生儿) 中,PREFUL是可行的.
结论:
- PREFUL MRI是一种经过验证的,没有对比剂的技术,用于定量V/Q成像.
- 在区域肺部疾病的检测,量化和治疗监测中提供帮助.
- 在临床常规和预测移植结果方面,PREFUL显示了潜在的附加值.
相关概念视频
Radiological Investigation II: MRI and Ventilation Perfusion Scan
107
Description
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
107
Magnetic Resonance Imaging
5.0K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
5.0K
Ventilatory Modes
94
Mechanical ventilators are life-saving devices that support or replace spontaneous breathing. They deliver breaths to patients through varying methods known as ventilator modes. Understanding these modes is critical for healthcare providers managing patients with respiratory failure.
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
94
Radiological Investigation III: Pulmonary Angiogram and PET Scan
88
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
88
Assessment of Diffusion and Perfusion
949
Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this...
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this...
949


