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Updated: Jun 15, 2025

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标记CC化学受体2用多功能细胞内体探针进行标记

Lisa S den Hollander1, Bert L H Beerkens1, Sebastian Dekkers1

  • 1Leiden Academic Centre for Drug Research, Division of Medicinal Chemistry, Leiden 2333 CC, The Netherlands.

ACS chemical biology
|August 26, 2024
PubMed
概括

研究人员开发了基于亲和力的新型探针 (AfBPs) 来研究G蛋白合受体 (GPCRs),特别针对CCR2. 这些多功能AfBPs为药物发现和标验证提供了抗体的有希望的替代品.

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...
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