腹腔内垂体细胞瘤:一个说明性的案例
Takashi Hanyu1, Ryota Ishibashi1, Kazushi Kitamura1
1Departments of Neurosurgery, Medical Research Institute, Kitano Hospital, Osaka, Japan.
Journal of neurosurgery. Case lessons
|August 26, 2024
概括
腹腔内垂体细胞瘤是一种罕见的瘤,可以在不影响垂体茎的情况下发生. 这一案例凸显了它的潜在起源来自下丘脑,以及在手术期间管理出血的关键需要.
科学领域:
- 神经瘤学神经瘤学
- 内分泌学 在内分泌学.
- 神经外科 神经外科
背景情况:
- 皮图细胞瘤是一种罕见的质瘤,起源于神经细胞核或fundibulum中的皮图细胞.
- 通常在部和细胞上部区域发现,内垂体细胞瘤没有infundibular参与是非常罕见的.
研究的目的:
- 报告一种罕见的内腔垂体细胞瘤病例.
- 讨论它的起源,诊断挑战和手术管理.
- 审查关于静脉内垂体细胞瘤的文献.
主要方法:
- 一个69岁的老人患有渐进性痴呆症的案例介绍.
- 磁力共振扫描显示,前三室内有一个心室内质块,没有涉及部,细胞上部区域或fundibulum.
- 通过跨管跨管方法去除瘤,然后进行包括甲状腺转录因子-1 (TTF-1) 免疫组织化学和DNA甲基化概况在内的组织病理学分析.
主要成果:
- 一名69岁的男性出现了痴呆症和一个孤立的腹腔内质量.
- 组织病理学显示双极细胞具有TTF-1免疫反活性. 基因组甲基化分析支持在下垂体细胞瘤/颗粒细胞瘤/螺旋细胞瘤类中的诊断.
- 一项系统性审查只发现了之前报告的5例心室内垂体细胞瘤病例.
结论:
- 腹腔内皮质细胞瘤可以独立于infundibulum出现,可能来自下丘脑结核cinereum皮质细胞.
- 超血管性质需要仔细控制手术期间的出血,特别是在相邻的下丘脑.
- 这个案例扩大了对 pituicytoma 局部化和手术考虑的理解.
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