对患有同时出现的酒精使用障碍和创伤后应激障碍的退伍军人的行为激活:试点随机对照试验的基础和方法
Shannon M Blakey1, Amber K Alsobrooks2, Antonio A Morgan-López1
1RTI International, 3040 E. Cornwallis Rd, P.O. Box 12194, Research Triangle Park, NC 27709-2194, USA.
Contemporary clinical trials
|August 26, 2024
概括
这项试点研究比较了酒精使用障碍和PTSD的退伍军人行为激活 (BA) 和复发预防 (RP). 它探讨了BABA的研究.
科学领域:
- 精神病学和行为健康
- 临床心理学 临床心理学
- 军事和退伍军人卫生保健
背景情况:
- 同时出现的酒精使用障碍和创伤后应激障碍 (AUD/PTSD) 影响了近200万美国退伍军人.
- 目前的AUD/PTSD治疗往往优先考虑减轻症状而不是心理社会功能,并且有很高的退学率.
- 现有的心理社会功能评估仅依赖于自我报告,限制客观测量.
研究的目的:
- 进行一项试点随机对照试验,将AUD/PTSD退伍军人的行为激活 (BA) 与复发预防 (RP) 进行比较.
- 评估BA作为AUD/PTSD治疗的可行性和可接受性.
- 探索BA和RP的初步疗效,包括使用地理空间数据对治疗反应的客观测量.
主要方法:
- 一个1:1平行,双臂试点随机对照试验,涉及46名患有AUD/PTSD的退伍军人.
- 每周八个虚拟单独的BA或RP心理治疗课程.
- 通过临床面试,自我报告和治疗前后的新型地理空间评估收集数据.
主要成果:
- 该研究的重点是试验可行性和初步疗效,结果正在等待.
- 地理空间分析将调查客观的治疗反应测量.
- BA的可接受性将成为一个关键的结果指标.
结论:
- 这项试验可能为患有AUD/PTSD的退伍军人提供更可接受的治疗选择.
- 积极的研究结果可能会支持未来在AUD/PTSD的平民中对BA的试验.
- 新的地理空间方法可以在临床研究中为AUD/PTSD恢复提供客观措施.
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