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Updated: Jun 15, 2025

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors
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从基于HPMCAS的无形固体分散物中探索利托纳维尔的生物相关条件和释放概况

Pradnya Bapat1, Robert Schwabe2, Shubhajit Paul2

  • 1Department of Industrial and Molecular Pharmaceutics, College of Pharmacy, Purdue University, West Lafayette, IN 47907, United States.

Journal of pharmaceutical sciences
|August 26, 2024
PubMed
概括

开发无形固体分散 (ASD) 的生物相关释放试验至关重要. 缓冲区的选择显著影响药物释放,表面pH值差异解释了不同的释放率,并影响了生物可访问性评估.

关键词:
无形固体的分散性固体.生物相关性 生物相关性释放性能 释放性能 释放性能表面的pH值是什么

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