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产前管理:早期母亲和新生儿的结果

Maria Luisa Imaz¹, Mercè Torra², Klaus Langohr³

¹Perinatal Mental Health Clinic-BCN Unit, Department of Psychiatry and Psychology, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Department of Medicine, Institute of Neuroscience, University of Barcelona (UB), Barcelona, Spain.

Journal of affective disorders

|August 26, 2024

概括

在分娩前短暂停用导致母亲的轻微波动和频繁的,短暂的新生儿效应,如低血压. 在怀孕的个体中,完全通过胎盘转移.

科学领域:

围产阶段的精神病学
孕产妇和胎儿的医学
新生儿药理学新生儿药理学

背景情况:

怀孕期间使用需要谨慎管理,以平衡母亲的心理健康和新生儿安全.
以前的建议建议在分娩前24-48小时减少30-50%的剂量或停止治疗,以尽量减少新生儿并发症.
了解母亲的水平,胎盘转移和新生儿结果对于优化围产期护理至关重要.

研究的目的:

为了调查母亲在短暂停药后分娩时的水平.
为了评估在分娩时的的胎盘转移.
确定新生儿水平与急性新生儿结局之间的关联.

主要方法:

一个教学医院的回顾性观察队列研究 (2006年11月 - 2018年12月).
纳入标准:稳定的妇女,单独怀孕,怀孕后期的治疗,分娩时的母亲和新生儿水平.
在预定分娩前12小时或在住院时停止服用;在分娩后6-12小时重新开始.

主要成果:

分析了66对母婴对;记录了226名母亲和66名新生儿的水平.
观察到轻微的母体的波动 (~0.20mEq/L),早期产后复发率为6%.
平均带/母亲产妇内比为1.10 (0.17). 56%的新生儿有过渡性急性并发症,最常见的是低血压 (N=15).
患有低血压的新生儿的平均水平显著更高 (0.178 mEq/L高,p=0.028).

结论:

表明完全通过胎盘转移.
在分娩前短暂停用与母亲水平的轻微波动有关.
在子宫内接触的新生儿经常经历过渡性急性影响,包括低血压.

关键词:

双极性障碍是一种双极性障碍.母亲母亲母亲母亲母亲新生儿新生儿新生儿周围部分 (peripartum) 是一个周围部分.胎盘通道是胎盘的通道.和是的组成部分.

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