膝关节完全置换后的甲状腺疾病:一个多中心,倾向性得分匹配的队列研究
Chen-Pi Li1, Shao-Wei Lo2, Christine Hsu3
1Department of Nursing & Tungs' Taichung MetroHarbor Hospital, Taichung, Taiwan, R.O.C.
In vivo (Athens, Greece)
|August 26, 2024
概括
全膝关节置换 (TKR) 手术可能会增加患甲状腺疾病的风险,特别是在老年人和女性中. 需要进一步的研究来了解这种联系,并制定预防策略.
科学领域:
- 内分泌学 在内分泌学.
- 整形外科手术 整形外科手术
- 公共卫生 公共卫生
背景情况:
- 甲状腺疾病是影响整体健康的常见内分泌疾病.
- 以前的研究重点是甲状腺功能障碍影响全膝关节置换 (TKR) 结果.
- 在TKR手术后发展甲状腺疾病的风险以前没有被调查.
研究的目的:
- 调查全膝关节置换 (TKR) 与随后患甲状腺疾病的风险之间的潜在关联.
- 为了比较接受TKR治疗的患者与没有接受TKR治疗的患者的甲状腺疾病发病率.
主要方法:
- 利用来自TriNetX研究网络 (2005-2018) 的电子医疗记录.
- 将TKR的骨关节炎患者与匹配的非TKR对照组进行比较.
- 员工倾向得分与对照对混因子和甲状腺疾病发展的评估危险比率相匹配.
主要成果:
- 与非TKR对照组相比,TKR患者患甲状腺疾病的风险明显高 (调整后HR=1.126).
- 在女性TKR患者和65岁及以上患者中,风险增加尤为明显.
- 分层分析证实,在这些特定的人口群体中,TKR后甲状腺疾病风险增加.
结论:
- 这项研究表明TCR与甲状腺疾病风险增加之间存在潜在联系.
- 老年人和女性似乎在TKR之后面临更高的风险.
- 需要进一步的研究来探索潜在的机制,并为TCR患者的临床监测和预防策略提供信息.
关键词:
甲状腺是什么?甲状腺是什么?队列 队列 队列 队列电子医疗记录 电子医疗记录流行病学流行病学甲状腺功能过强症 甲状腺功能过强症甲状腺功能低下症 甲状腺功能低下症甲状腺疾病是一种甲状腺疾病.整体膝关节置换 整体膝关节置换更多相关视频
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