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骨年龄成熟度与儿童脂肪度之间的关联
Ana Gabriela Chávez-Vázquez1, Miguel Klünder-Klünder1, Desiree Lopez-Gonzalez2
1Unit of Epidemiological Research in Endocrinology and Nutrition, Hospital Infantil de México Federico Gómez, Mexico City, Mexico.
Pediatric obesity
|August 26, 2024
概括
儿童体脂肪增加与骨老化 (BA) 有关. 这项研究发现,超重和肥胖的墨西哥儿童,尤其是男孩,比正常体重的同龄人更早达到高级BA.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 儿童肥胖研究儿童肥胖研究
- 骨发育研究 骨发育研究
背景情况:
- 超重和肥胖是已知的骨衰老 (BA) 的风险因素.
- 了解肥胖对骨成熟的影响对于儿科健康至关重要.
- 以前的证据表明,体重过重和骨发育加速之间存在相关性.
研究的目的:
- 为了研究肥胖对墨西哥儿童骨年龄的特定影响.
- 量化各种脂肪和高级BA的各种测量之间的关联.
- 为儿童群体提供关于身体组成和骨成熟之间的关系的见解.
主要方法:
- 一项涉及902名墨西哥5至18岁儿童的横截面研究.
- 利用人体测量,双能X射线吸收计 (DXA) 测量身体组成,以及自动手部X射线进行BA评估.
- 分析了身体质量指数 (BMI),腰高比和DXA衍生的脂肪质量与高级BA之间的关联,计算了赔率比.
主要成果:
- 超重/肥胖儿童 (BMI SDS ≥1) 与体重正常的儿童相比,BA进展显著提前 (p < 0.01).
- 较高的体脂百分比 (DXA SDS ≥1) 也与男孩和女孩的早期晚期BA有关 (p < 0.01).
- 增加的BMI或DXA衍生的脂肪性 (SDS ≥1) 与具有BA超过一年的更大概率 (OR 1.79-3.55,p < 0.05) 相相关.
结论:
- 增加脂肪,特别是在男孩中,与儿童的骨年龄显著相关.
- 这些发现突出了多余的身体脂肪对加速骨成熟的影响.
- 这种关联强调了管理儿童肥胖的重要性,以实现最佳的生长和发展.
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