在美国的老年人中,生命的基本8和认知功能之间的关联
Huaxin Zhu1, Bo Hei1,2, Wu Zhou1
1Department of Neurosurgery, the 1st Affiliated Hospital, Jiangxi Medical College, Nanchang University, No. 17 Yongwaizheng Street, Nanchang, 330006, Jiangxi, China.
Scientific reports
|August 26, 2024
概括
通过Life's Essential 8 (LE8) 测量较高的心血管健康,与老年人更好的认知功能有关. 保持良好的心脏健康可能会支持老年人的大脑健康和记忆力.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 公共卫生 公共卫生
背景情况:
- 美国心脏协会重新定义了心血管健康 (CVH) 生命的基本8 (LE8),包括饮食,活动,尼古丁,睡眠,BMI,胆固醇,葡萄糖和血压.
- 认知功能对老年人的生活质量至关重要,其下降是一个重大的公共卫生问题.
研究的目的:
- 调查美国老年人的总和个体生命必需8 (LE8) 度量与认知功能之间的关联.
- 为了确定更好的心血管健康是否与这一人口群体的增强认知表现有关.
主要方法:
- 美国国家健康和营养检查调查 (NHANES) 数据 (2011-2014) 的横截面分析,来自60岁以上的美国成年人.
- 用CERAD,动物流利性和数字符号替换测试来评估认知功能.
- 用于分析LE8分数 (分为低,中等,高) 和认知测试结果之间的关联的多变量后勤和受限立方线模型.
主要成果:
- 在2279名参与者中,只有11%的人达到高CVH (LE8得分80-100),而12%的人具有低CVH (0-49).
- 较高的LE8分数显示出显著的,线性,剂量反应关联与所有认知功能测试 (CERAD延迟回忆,CERAD总数,动物流利性,数字符号) 的改善分数.
- 在个体LE8健康行为和健康因素得分和认知功能之间观察到正线性关系.
结论:
- 根据Life's Essential 8的定义,较高的心血管健康水平与美国老年人的更好的认知功能有关.
- 这些发现表明,促进心血管健康可能是支持老年人群认知功能的策略.
- 需要进一步的研究来确定LE8指标与认知功能之间的因果关系和时间关系.
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