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Updated: Jun 15, 2025

Author Spotlight: Advancing Antibiotic Resistance Research Using an Efflux-Deficient Bacterial Strain and a Single-Copy Gene Expression System
05:06

Author Spotlight: Advancing Antibiotic Resistance Research Using an Efflux-Deficient Bacterial Strain and a Single-Copy Gene Expression System

Published on: January 5, 2024

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在TolC的结构性变化促进了Efflux-Mediated β-lactam抵抗

Isik Kantarcioglu1,2, Ilona K Gaszek2, Tandac F Guclu1

  • 1Faculty of Engineering and Natural Sciences, Sabancı University, Tuzla, Istanbul, Turkey.

Communications biology
|August 26, 2024
PubMed
概括

流动性抗生素耐药性是一个主要的威胁. 这项研究揭示了TolC排泄如何促进细菌对β-乳糖抗生素的耐药性,为新药开发提供了目标.

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