基于长期结果的门高血压肠道病变恶化的预测因素
Yuka Matsubara1, Akiyoshi Tsuboi2,3, Issei Hirata1
1Department of Gastroenterology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
BMC gastroenterology
|August 26, 2024
概括
门性高血压肠道病变 (PHE) 可以随着时间的推移而恶化,特别是在加剧的食道变节. 监测PHE对于预防风险患者的胃肠道出血至关重要.
科学领域:
- 胃肠病学 胃肠病学
- 肝病学 肝病学是一种肝病学.
- 内镜检查是指内镜检查.
背景情况:
- 门性高血压肠道病变 (PHE) 是一种小肠状况,与门性高血压有关.
- 在PHE中内镜发现的临床意义需要进一步澄清.
研究的目的:
- 确定囊内镜检查结果在PHE患者中的临床意义.
- 通过使用长期结果,确定PHE恶化的预测因素.
主要方法:
- 一项对55名PHE患者的回顾性研究使用囊内镜 (CE) 进行了超过3年的随访.
- 评估影响PHE恶化和它们对胃肠道出血的影响的临床因素.
主要成果:
- 35%的患者在随访CE时出现PHE恶化.
- 严重的PHE与食道静脉变异恶化 (32%),纤维化-4指数较高 (21%) 和门脉高压胃 (42%) 相关.
- 食道静脉的恶化和没有切除术是PHE恶化的显著预测因素,与增加的胃肠道出血风险相关.
结论:
- 加重的食道静脉和缺少切除术与PHE恶化有显著的相关性.
- 患有PHE恶化的患者需要密切监测,以防止胃肠道出血.
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