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患有中风或过渡性缺血性发作患者的深静脉血栓形成:一项追溯观察性研究

Charlotte Huber¹, Stephan Stöbe², Andreas Hagendorff²

¹Department of Neurology, University of Leipzig, Liebigstr. 20, 04103, Leipzig, Germany.

|August 26, 2024

概括

深静脉血栓形成 (DVT) 发生在大量中风患者中,这些患者有 patent foramen ovale (PFO). 威尔斯评分可以帮助识别需要进一步查DVT的患者.

科学领域:

心脏病学心脏病学
神经学神经学
血管医学血管医学

背景情况:

卵孔 (PFO) 与导致脑缺血的悖论性栓塞有关.
深静脉血栓塞 (DVT) 是PFO患者血栓塞的潜在来源,但查率各不相同.
由于缺乏明确的指导方针,因此需要描述PFO中风/TIA患者的DVT患病率.

研究的目的:

确定中风或暂时性缺血性发作 (TIA) 和PFO患者的DVT的发生率.
在这个人群中确定与DVT相关的临床,人口和实验室参数.
评估风险评分在预测DVT中的有用性.

主要方法:

对中风/TIA和PFO患者的医疗记录进行了回顾性分析.
通过下肢压缩超声波进行DVT诊断.
在DVT+和DVT-组之间比较人口统计,临床,实验室数据,RoPE和威尔斯分数.

主要成果:

确定了339名中风/TIA和PFO患者 (61.2±15.4岁,61.1%男性).
在接受超声波检查的患者中,检测到7.8% (17/217) 的DVT.
严重的DVT与以前的严重的DVT,癌症,固定,小腿疼痛/胀以及D-二次数升高有关. 威尔斯分数是一个显著的预测指标 (OR 35.46).

结论:

在患有脑缺血和PFO的患者中,DVT存在于相当比例的患者中.
在这些患者的诊断工作中,应考虑对DVT进行查.
威尔斯评分可以有效指导压缩超声波的需要.

关键词:

深静脉血栓形成的原因之一是深静脉血栓.缺血性中风是因为缺血性中风.专利对于形形的人.过渡性缺血性攻击是短暂的

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