成人再综合征发展的危险因素:系统性审查
Ping Zheng1, Yilin Chen2, Feng Chen3
1Department of Nursing, PengZhou People's Hospital, Chengdu, Sichuan, China.
概括
识别患有再养综合征 (RFS) 高风险的患者至关重要. 关键的风险因素包括滥用酒精,癌症,高血压和特定的临床评分,指导更好的RFS预测和预防策略.
科学领域:
- 临床营养学 临床营养学
- 临界护理医学 临界护理医学
- 医疗信息学 医疗信息学
背景情况:
- 再养综合征 (RFS) 对易受伤害的患者构成重大风险.
- 准确识别患有RFS高风险的患者对于及时实施预防措施至关重要.
- 目前对RFS的临床决策和风险预测工具需要对相关风险因素有更深入的了解.
研究的目的:
- 进行系统性审查,以确定和整合已知的再养综合征 (RFS) 发展的风险因素.
- 为改进临床决策流程,风险预测模型和RFS查工具的开发提供信息.
主要方法:
- 在PubMed,EMBASE,Cochrane图书馆和科学网络 (1990年1月 - 2023年3月) 的系统文献搜索.
- 包括调查人口,临床,药物使用,实验室和营养因素与RFS相关的研究.
- 使用纽卡斯尔-太华尺度对方法质量的评估.
主要成果:
- 包括30项研究,确定了与增加RFS风险相关的33个因素.
- 在多项研究中一致报告的因素包括:酒精滥用史,癌症,并发性高血压,高APACHE II和SOFA得分,低GCS得分,利尿剂使用,低基线前白蛋白,高基线肌素和肠道营养.
- 大多数纳入的研究 (66.7%) 的方法质量很高.
结论:
- 这一系统性审查突出了RFS的一些重要风险因素.
- 由于研究数量有限和对个别因素的高质量证据,需要进一步的研究和确认.
- 结果可以指导开发更有效的RFS风险分层和选工具.
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