口腔微生物群多样性和饮食质量与死亡率相关
Jie Shen1, Hui Chen1, Xiaofeng Zhou2
1School of Public Health, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Journal of clinical periodontology
|August 27, 2024
概括
保持多样化的口腔微生物组和高质量的饮食与较低的死亡风险有关. 这项研究强调了口腔健康和营养对死亡率结果的联合保护作用.
科学领域:
- 微生物组研究的研究.
- 营养科学 营养科学
- 公共卫生 公共卫生
背景情况:
- 口腔微生物群对整体健康起着至关重要的作用.
- 饮食质量是已知的慢性疾病和死亡率的决定因素.
- 了解口腔健康和饮食之间的相互作用对于预防性健康策略至关重要.
研究的目的:
- 研究口腔微生物群多样性和饮食质量对全因和因特定死亡率的独立和联合影响.
- 评估口腔微生物群多样性指标与死亡风险之间的关联.
- 评估饮食质量与死亡风险之间的关系.
主要方法:
- 分析了美国国家健康和营养检查调查 (NHANES) 中7055名成年人的数据.
- 使用阿尔法多样性指数测量口腔微生物群多样性 (辛普森指数,ASVs,Faith's PD,Shannon-Weiner).
- 通过2015年健康饮食指数 (HEI-2015) 评估饮食质量;用于分析的Cox比例危险模型.
主要成果:
- 更高的口腔微生物群多样性和更好的饮食质量独立地与减少全因死亡率有关.
- 无论是口腔微生物群多样性 (辛普森指数) 还是HEI-2015最高的三分动物中的个体,死亡风险都显著降低.
- 增加口腔微生物群的多样性与心脏代谢性疾病和癌症的死亡风险降低相关.
结论:
- 更高的口腔微生物群α多样性独立地与较低的死亡风险有关.
- 改善饮食质量与降低死亡风险独立相关.
- 高口腔微生物群多样性和良好的饮食质量的结合效应提供了对死亡率的显著保护.
相关概念视频
What is Monogastric Digestion?
70.9K
The human body contains a monogastric digestive system. In a monogastric digestive system, the stomach only contains one chamber in which it digests food. Several other animal species also have monogastric digestive systems, including pigs, horses, dogs, and birds. This chapter, however, focuses on the human digestive system.
70.9K
Anatomy of the Intestines
71.6K
Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
71.6K
Bacterial Flora of the Large Intestine
401
The gut microbiome is formed by a vast and diverse community of bacteria that colonizes our large intestine. These bacteria start residing in the gut from birth and continue diversifying throughout life, influenced by factors such as diet, lifestyle, and stress. The gut bacterial community also includes bacteria from food and those that enter the colon through the anus.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
401
Factors Affecting the Risk of Infection
11.5K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.5K


