在寒冷压力机任务中经历的实验性疼痛受到年轻成人女性血红蛋白水平的影响
Indu Saxena1, Manoj Kumar2, Nandini Srivastava2
1Department of Biochemistry, All India Institute of Medical Sciences, Gorakhpur, Gorakhpur, IND.
Cureus
|August 27, 2024
概括
贫血会增加疼痛感知和心血管对冷压力任务 (CPT) 疼痛的反应. 与非贫血个体相比,贫血个体报告疼痛评级较高,血压和心率变化更大.
科学领域:
- 疼痛感知研究 疼痛感知研究
- 心血管反应性研究的研究
- 贫血和健康结果.
背景情况:
- 个人的疼痛感知因生物,心理和社会因素而有所不同.
- 了解影响疼痛的因素在临床实践中至关重要.
- 贫血可能会改变一个人的疼痛感知.
研究的目的:
- 研究贫血对疼痛感知和心血管反应性的影响.
- 为了比较非贫血,轻度贫血和中度贫血组的疼痛反应.
主要方法:
- 研究涉及73名女性受试者:25名非贫血患者,24名轻度贫血患者,24名中度贫血患者.
- 使用冷压器任务 (CPT) 诱导的实验性疼痛.
- 通过心血管反应 (血压,心率) 和疼痛敏感性 (疼痛值,耐受性,评分) 评估疼痛反应.
主要成果:
- 贫血患者表现出更高的心血管对压力的反应性.
- 中度贫血显示静缩和静缩血压和心率的最高增加.
- 与非贫血患者相比,贫血患者报告的疼痛评级显著更高 (7.21),而非贫血患者 (6.44).
结论:
- 寒冷压力或任务诱导的疼痛导致贫血患者心血管反应性增加.
- 贫血与增加的疼痛感知有关,由更高的平均疼痛评级表明.
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Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.