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超声波检测SARS-CoV-2胎盘炎的迹象. 与怀孕结果的关联

Madalina Iordache¹, Adrian Dumitru², Natalia Turcan³

¹Doctoral School of "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.

|August 27, 2024

概括

孕妇的COVID-19感染可以加速胎盘衰老,导致快速成熟和衰老. 这种加快的衰老,特别是在诊断时成熟度为3级的胎盘中,可以导致胎盘不充分和子宫内生长限制 (IUGR).

科学领域:

产科和妇科产科和妇科
传染性疾病传染性疾病
医疗成像医学成像

背景情况:

SARS-CoV-2 感染可以影响多个器官,包括胎盘,导致一种称为 SARS-CoV-2 胎盘炎的情况.
这种胎盘炎的特征是周周纤维素沉积,慢性囊细胞间接炎和 trofhoblast 亡.
缺乏关于超声波发现和监测策略的公布数据,用于在SARS-CoV-2感染的胎盘中大量的周周纤维素沉积.

研究的目的:

为了分析第三季度感染SARS-CoV-2的孕妇胎盘的超声波外观.
为了将超声波发现与胎盘组织病理学和怀孕结果相关联.

主要方法:

在感染SARS-CoV-2的孕妇中,连续的产科超声波每周进行一次,直到分娩.
在所有病例中,产后进行了胎盘组织病理学检查.
评估的超声波参数包括胎盘成熟度,化和周周纤维素沉积的迹象.

主要成果:

在SARS-CoV-2感染女性的胎盘与子宫内生长限制 (IUGR) 显示在COVID-19诊断后三周内加速成熟和衰老.
每周观察到胎盘化的逐渐增加.
严重的胎盘恶化,导致胎盘缺陷和IUGR,在被纳入研究时,在怀孕妇女中发现了3级胎盘.

结论:

在SARS-CoV-2感染时胎盘成熟度增加与异常快速的胎盘衰老有关.
超声波评估可以识别胎盘衰老中的这些变化.
这些发现突显了超声波在COVID-19阳性怀孕中监测胎盘健康的潜力.

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