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Updated: Jul 24, 2026

gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair
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在接受乳腺癌治疗的患者中进行基因检测的单一中心经验

Laura Mihaela Mustata1, Gheorghe Peltecu1,2, Diana Cezara Mugescu1

  • 1Filantropia Clinical Hospital, Gynecology Department, Bucharest, Romania.

Maedica
|August 27, 2024
PubMed
概括

乳腺癌患者的生殖基因突变,特别是那些被诊断为50岁以下的三阴性疾病患者,从量身定制的遗传评估和治疗中受益. 这种个性化的方法改善了病原体变异载体的管理和长期结果.

关键词:
这就是BRCA1的原因.这就是BRCA2的原因.乳腺癌 乳腺癌 乳腺癌癌症易感性基因 癌症易感性基因发生生殖线突变的生殖线突变.降低风险的预防性手术.

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Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...