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Updated: Jun 15, 2025

Identifying Amino Acid Overproducers Using Rare-Codon-Rich Markers
10:41

Identifying Amino Acid Overproducers Using Rare-Codon-Rich Markers

Published on: June 24, 2019

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一种统计物理方法来优化编码子使用

David Luna-Cerralbo1,2, Irene Blasco-Machín3, Susana Adame-Pérez3

  • 1Department of Theoretical Physics, Faculty of Science, University of Zaragoza, c/ Pedro Cerbuna s/n, Zaragoza, 50009, Spain.

Computational and structural biotechnology journal
|August 27, 2024
PubMed
概括

一个新的统计物理模型,即近邻 (NN) 模型,通过考虑子相互作用来优化蛋白质表达. 这种方法在体内显著提高了蛋白质的生产,为生物技术和mRNA疗法提供了优势.

关键词:
编码优化 - 编码优化最接近邻居的互动.蛋白质表达方式 蛋白质表达方式统计物理模型的模型.这是一种mRNA疫苗.

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