睡眠中的性别差异和睡眠呼吸障碍
Esther I Schwarz1,2, Sophia Schiza3
1Department of Pulmonology and Sleep Disorders Centre, University Hospital Zurich.
Current opinion in pulmonary medicine
|August 27, 2024
概括
人们越来越认识到睡眠呼吸障碍 (SDB) 的性别差异. 研究表明,与男性相比,女性的SDB表型和症状不同,因此需要进一步研究针对性治疗.
科学领域:
- 睡眠医学 睡眠医学
- 呼吸系统医学 呼吸系统医学
- 健康中的性别差异
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 在其病理生理学,症状表现和患者结果方面表现出显著的性别差异.
- 对睡眠呼吸障碍 (SDB) 中的性别特异现象的研究仍处于早期阶段,对非OSA SDB条件的数据有限.
研究的目的:
- 审查关于睡眠呼吸障碍 (SDB) 性别差异的现有证据.
- 突出需要进一步研究SDB的性别特异性表型,以改善治疗策略.
主要方法:
- 关于睡眠呼吸障碍中的性别差异现有文献的综述.
- 基于性别的患病率,病理生理学和症状表现的分析.
主要成果:
- 虽然OSA在男性中比绝经前妇女更为普遍,但其在绝经后妇女中的患病率与男性相等.
- 女性表现出较低的上呼吸道折叠性和兴奋值,在较低的呼吸暂停-呼吸暂停指数 (AHI) 水平上经常出现更多症状.
- 特定的OSA形式,如REM-OSA和像COMISA这样的表型在女性中更为常见,而男性患中央睡眠呼吸暂停的风险更高.
结论:
- 了解性别典型的SDB表型对于开发有针对性的治疗方法至关重要.
- 专注于SDB性别差异的充足的研究对推进该领域至关重要.
相关概念视频
Sleep Apnea
131
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
The condition is more prevalent among...
131
Substance Use Disorders Affecting Sleep
163
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
163
Insufficient Sleep and Sleep Deprivation
137
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
Sleep deprivation is a more severe form of sleep loss...
137
Sleep-Wake Cycles
1.2K
Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
1.2K
Sleepwalking and Sleep Talking
132
Somnambulism, commonly known as sleepwalking, involves individuals engaging in activities ranging from simple walking to more complex behaviors such as driving. Sleepwalking typically occurs during the slow-wave sleep stages 3 and 4 early in the night when the person is not dreaming, contradicting the myth that sleepwalkers are acting out their dreams.
Factors that increase the likelihood of sleepwalking include sleep deprivation and alcohol consumption. Contrary to common beliefs, it is safe...
Factors that increase the likelihood of sleepwalking include sleep deprivation and alcohol consumption. Contrary to common beliefs, it is safe...
132
REM Sleep Behavior Disorder
163
REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
RBD is significantly associated with...
163


