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侧侧头骨基骨质放射性死:一个15年的连续20个连续病例和建议的管理方案

Emma Richards¹, Jameel Muzaffar¹, Raghu Kumar¹

¹ENT Department, Queen Elizabeth Hospital Birmingham, University Hospital Birmingham NHS Foundation Trust, Birmingham, UK.

The Journal of laryngology and otology

|August 27, 2024

概括

骨骨质放射性死 (TBON) 是一种严重的辐射并发症. 早期的TBON可以保守地管理,但耐火病例需要多学科的团队方法,包括对危及生命的内败血症进行手术.

科学领域:

耳鼻喉科耳鼻喉科耳鼻喉科
神经外科神经外科
辐射瘤学辐射瘤学

背景情况:

暂时性骨性骨性瘤 (TBON) 是头癌的放射治疗后的一种罕见但严重的并发症.
目前对TBON的管理策略缺乏标准化的协议,导致治疗结果多样化.

研究的目的:

审查15年来对TBON的管理.
突出多学科团队 (MDT) 在管理TBON中的作用.
为未来的TBON案件推导一个管理协议.

主要方法:

20名患有TBON的患者的回顾性病例审查.
对MDT管理策略的分析.
与现有文献进行比较,以制定方案.

主要成果:

TBON影响了外部听觉通道,中耳和骨侧底部.
呈现的症状包括疼痛,感染,神经病变和内败血症.
治疗范围从高压氧和抗生素到手术切除和组织移植.

结论:

早期的TBON可能会对保守的管理做出反应.
耐火性TBON由于内并发症和败血症而带来危及生命的风险.
先进的TBON需要一种MDT方法,包括彻底的手术和血管化的组织重建.

关键词:

头部和部的新生瘤.骨质放射性衰老 (osteoradionecrosis) 是一种严重的疾病.放射学放射学是指放射学辐射疗法辐射疗法骨的时间骨.

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