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Updated: Jun 15, 2025

Generation of Cancer Cell Clones to Visualize Telomeric Repeat-containing RNA TERRA Expressed from a Single Telomere in Living Cells
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Generation of Cancer Cell Clones to Visualize Telomeric Repeat-containing RNA TERRA Expressed from a Single Telomere in Living Cells

Published on: January 17, 2019

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TERRA招募和凝结到端粒的分子机制

Bersabel Wondimagegnhu1,2, Wen Ma3, Tapas Paul2

  • 1Program in Cell, Molecular, Developmental Biology and Biophysics, Johns Hopkins University, Baltimore, MD 21218, USA.

Nucleic acids research
|August 27, 2024
PubMed
概括

包含RNA的端粒重复 (TERRA) 动态入侵端粒,形成一个稳定的三重结构. 庇护蛋白TRF2和RAD51促进了这一过程,而TRF1则抑制了这一过程,揭示了TERRA-端粒相互作用的关键机制.

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