鉴定和量化银杏花叶中的抗氧化剂
Chenxiu Hu1,2, Yujing Wang1, Yingqian Deng1
1College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
Biomedical chromatography : BMC
|August 27, 2024
概括
银杏花叶提取物 银杏花叶提取物
科学领域:
- 植物化学 植物化学
- 药理学是指药理学,即药理学是指药理学.
- 分析化学 分析化学
背景情况:
- 银杏叶 (GBL) 提取物的抗氧化特性与其治疗作用有关.
- 各个GBL成分的特定抗氧化活性需要澄清.
研究的目的:
- 为了识别和量化GBL中的抗氧化化合物.
- 建立一种分析GBL中主要抗氧化剂的方法.
主要方法:
- 超高性能液态色谱-四极飞行时间质谱 (UPLC-QTOF-MS) 用于成分识别.
- 氧基吸收能力 (ORAC) 试验用于抗氧化活性的确定.
- 高性能液体染色学 (HPLC) 用于定量分析.
主要成果:
- 确定了194个GBL成分,包括97个黄类和37个类.
- 36个成分,主要是黄和碳酸,显示出高的抗氧化活性.
- 凯姆菲罗尔3-O-β-D-(6′′-p-coumaroyl) 葡萄皮拉诺西尔-(1-2) -α-L-rhamnopyranoside,凯姆菲罗尔-3-O-rutinoside和鲁丁是丰富的和高度活跃的.
结论:
- 在GBL中确定了关键的抗氧化化合物,特别是特定的黄类化合物.
- 开发了一种可靠的HPLC方法来量化主要的抗氧化剂.
- 结果支持GBL在药品和健康产品中的使用.
相关概念视频
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