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Updated: Jun 15, 2025

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测试用于表征表面的吸附性质 (APS).

Bente Siebels1, Manuela Moritz1, Diana Hübler2

  • 1Section Mass Spectrometry and Proteomics, University Medical Center Hamburg-Eppendorf, Martininstr. 52, Hamburg, 20246, Germany.

Chemistry (Weinheim an der Bergstrasse, Germany)
|August 27, 2024
PubMed
概括

在样本准备过程中,分析剂对表面的吸附会导致样本损失. 这种新的试验量化了吸附相互作用,有助于最大限度地减少分析物损失,并提高了omics数据的准确性.

关键词:
吸附取决于分子的损失.溶解分子与表面的相互作用.基于LCMS/MS的无标签量化

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In certain chromatographic separations, solutes transfer between the mobile phase and the stationary phase via sorption, which typically refers to the process of adsorption. For many chromatographic systems, the sorption process often depends on the polarity of the compounds—an expression of the overall dipole moment within the molecule. During the separation process, there is competition between the solute and solvent for adsorption to the stationary phase. Highly polar compounds and...
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