血友病男性和女性患者患者报告结果的差异和相似之处
Christine L Kempton1,2, Sara A Guasch3, Tyler W Buckner4
1Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, Georgia, USA.
概括
与男性相比,患有血友病的女性报告的抑郁,焦虑和疲劳率更高. 这凸显了在照顾患有这种出血障碍的妇女方面,迫切需要综合心理健康支持.
科学领域:
- 血液学 血液学 血液学
- 精神病学是一个精神病学.
- 患者报告的结果
背景情况:
- 血友病影响男性和女性,有潜在不同的经验.
- 了解血友病患者经历中的基于性别的差异对于量身定制的护理至关重要.
研究的目的:
- 为了比较患者报告的男性和被诊断患有血友病的女性之间的结果.
- 为了确定血友病患者在生活质量,心理健康和身体健康方面的基于性别的差异.
主要方法:
- 从血友病相关的痛苦问卷验证研究中对数据进行横截面的后期分析.
- 包括来自两个治疗中心的139名患有血友病A或B的成年人 (≥18岁).
- 使用未调整和多变量线性回归来分析结果中的性别差异.
主要成果:
- 女性 (n=21) 报告的抑郁症 (PHQ-9),焦虑和疲劳 (PROMIS-29) 评分明显高于男性 (n=118).
- 大多数参与者患有A型血友病 (89.2%);女性更有可能患有轻度血友病 (85.7%vs26.3%).
- 在其他测量健康结果中没有观察到任何显著的性别差异.
结论:
- 患有血友病的女性比男性更容易经历抑郁,焦虑和疲劳.
- 综合心理健康服务对于患有血友病的女性至关重要.
- 进一步的研究应该探索血友病和无血友病妇女的比较心理健康及其临床影响.
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