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Updated: Jun 15, 2025

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用利科哈尔康D向STING的寡合化改善了STING驱动的炎症性疾病

Yinghui Zhang1,2, Yadan Liu1,3, Bing Jiang3

  • 1Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.

Science China. Life sciences
|August 27, 2024
PubMed
概括

使用人工智能模型发现了一种新的STING抑制剂Licochalcone D (LicoD). 利科德 (LicoD) 协同修改了STING,在炎症性疾病和癌症的小鼠模型中减少了炎症.

关键词:
利科哈尔科尼 D D这是一种STING抑制剂.变压器CPI模型cGAS-STING信号传输系统提供信号.炎症性疾病是一种炎症性疾病.

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