在马的口腔T细胞丰富的大B细胞淋巴瘤
Jéssica Cristina Peretti1, Aline Bielak Dos Santos1, Ezequiel Davi Dos Santos1
1Laboratory of Animal Pathology, Program in Bioexperimentation, School of Agricultural Sciences, Innovation and Business, UPF, Passo Fundo, Rio Grande do Sul, Brazil.
Veterinary research communications
|August 27, 2024
概括
本报告详细介绍了一种罕见的T细胞丰富的口腔大B细胞淋巴瘤病例. 侵袭性瘤透到面部骨,鼻和周围组织,导致严重的临床症状.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 在瘤学瘤学.
- 马的健康 马的健康
背景情况:
- 淋巴瘤是马中最常见的造血性瘤.
- 马类淋巴瘤的临床表现因瘤的位置和程度而异.
- 口腔淋巴瘤很少见,但可能导致严重的局部入侵.
研究的目的:
- 描述一种富含T细胞的口腔大B细胞淋巴瘤在马的病例.
- 详细介绍这个特定的马类淋巴瘤的临床,病理和组织学发现.
- 为了强调这种瘤类型的侵略性和侵入性潜力.
主要方法:
- 对25岁的克里乌拉马匹进行临床检查,发现脸部胀和呼吸困难.
- 诊断成像以评估病变的位置和程度.
- 对受影响的组织进行粗体解剖检查.
- 瘤样本的组织病理学分析,包括CD20和CD3标记物的免疫组织化学.
主要成果:
- 一只25岁的母马出现了面部胀,呼吸不全,厌食症和体重减轻.
- 口腔瘤广泛透到正面/尾巴鼻,头骨,硬 palatus,和按摩器肌肉.
- 组织病理学证实了富含T细胞的大B细胞淋巴瘤,其特征是CD20+新发性B细胞和CD3+反应性T细胞.
结论:
- 富含T细胞的口腔大B细胞淋巴瘤可能是马中的一种侵略性和高度侵入性的瘤.
- 早期诊断和了解侵袭程度对于管理马匹口腔淋巴瘤至关重要.
- 这一案例凸显了马匹异常口腔质量的彻底诊断工作的重要性.
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