中国草药在良性前列腺增生症的机制和有效性
Fu Wang1, Dong-Yue Ma1, Jiu-Tian Yang2
1Department of Andrology, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing, 100091, China.
Chinese journal of integrative medicine
|August 27, 2024
概括
中国草药 (CHM) 为良性前列腺增生 (BPH) 提供了一种多目标方法,可能调节激素,减少炎症和改善尿路症状 (LUTS). 这种疗法对有效管理BPH有希望.
科学领域:
- 药理学 药理学是指药理学的学科.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 综合医学是一个整体医学.
背景情况:
- 良性前列腺增生 (BPH) 是老年男性中普遍存在的疾病,导致下泌尿道症状 (LUTS),损害生活质量.
- 在不同地区,中国草药 (CHM) 经常用于BPH治疗.
研究的目的:
- 审查CHM在治疗BPH中的分子机制.
- 评估CHM在BPH管理中的疗效和安全性的临床证据.
主要方法:
- 在2023年12月31日之前对32个英语同行评审出版物 (PubMed, Web of Science) 进行系统审查.
- 分析包括体外,体内 (动物/细胞) 研究和4项临床试验/元分析.
主要成果:
- 药物可以通过调节性激素,抑制细胞增殖,促进细胞亡,减少炎症和施加抗氧化作用来治疗BPH.
- 药物表现出潜在的α-阻断剂类作用,放松尿道光滑肌,缓解LUTS.
- 临床数据表明,CHM对BPH是安全有效的,提供多组分,多目标的治疗效益.
结论:
- 合并治疗是一种有前途的,多面的BPH治疗策略.
- 治疗CHM可以减轻BPH的严重程度,改善LUTS,并可能成为可靠的未来治疗选择.
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