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Updated: Jun 15, 2025

Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia
10:49

Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia

Published on: September 18, 2013

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销售前关键试验终点和FDA突破性疗法市场营销后要求

Maryam Mooghali1,2, Joshua D Wallach2,3, Joseph S Ross1,2,4,5

  • 1Section of General Internal Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut.

JAMA network open
|August 27, 2024
PubMed
概括

突破性治疗指标通常依赖于代用标记,即使是传统的批准. 要求对这些适应症进行营销后研究可以提高对患者和临床医生的临床益处的确定性.

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