准STIM1有助于缓解动脉样硬化中血管光滑肌细胞的重塑

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Updated: Jun 15, 2025

Murine Aortic Crush Injury: An Efficient In Vivo Model of Smooth Muscle Cell Proliferation and Endothelial Function
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Murine Aortic Crush Injury: An Efficient In Vivo Model of Smooth Muscle Cell Proliferation and Endothelial Function

Published on: June 11, 2017

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Zhenyu Cui1, Yue Zhang1, Lezhi Sheng1

  • 1Department of Cardiovascular Medicine, Shanghai Pudong New Area People's Hospital, 201299 Shanghai, China.

Discovery medicine
|August 27, 2024
PubMed
概括

流体相互作用分子1 (STIM1) 缺乏抑制血管光滑肌细胞 (VSMC) 重塑和动脉样硬化通过抑制Orai1. 这一发现凸显了STIM1作为心血管疾病的潜在治疗点.

关键词:
奥赖释放激活调节器 1动脉样硬化 动脉样硬化流体相互作用分子 1 1血管光滑肌肉细胞的细胞.

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