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Updated: Jun 15, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

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Rh(III) - 催化 [3 + 3] - 合 3-氧化和碳酸的循环反应:快速获得螺旋乳酸骨架

Chengjie Wang1, Huanfeng Jiang1, Wei Zeng1

  • 1Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510641, China.

Organic letters
|August 27, 2024
PubMed
概括

一种新的Rh(III) 催化反应有效地从简单的前体中产生复杂的螺旋环化合物. 这种方法为新型多功能化-spiro[isochromene-1,1′-isoindolin]-3′-ones提供了有价值的合成途径.

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Cyclohexenones via Michael Addition and Aldol Condensation: The Robinson Annulation

Robinson annulation is a base-catalyzed reaction for the synthesis of 2-cyclohexenone derivatives from 1,3-dicarbonyl donors (such as cyclic diketones, β-ketoesters, or β-diketones) and α,β-unsaturated carbonyl acceptors. Named after Sir Robert Robinson, who discovered it, this reaction yields a six-membered ring with three new C–C bonds (two σ bonds and one π bond).
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