案例报告:印度的坎皮洛巴克特菌菌病
Srived Meda1,2, Padmaja Shenoy3, Gauri Kumar3
1Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, India.
The American journal of tropical medicine and hygiene
|August 27, 2024
概括
坎皮洛巴克特菌病,通常与肝脏疾病有关,在印度患者中呈现独特,发烧和腹痛比腹更常见. 这项研究强调了它通过新的血液培养基的检测.
科学领域:
- 传染性疾病 传染性疾病
- 肝病学 肝病学是一种肝病学.
- 微生物学 微生物学
背景情况:
- 胃肠炎是Campylobacter spp.的典型表现. 感染. 感染.
- 侵袭性感染,如Campylobacter bacteremia,报告的频率较低.
- 坎皮洛巴克特细菌病例不常见,特别是在患有潜在慢性肝病的患者中.
研究的目的:
- 报告和描述来自印度一家三级医院的12例Campylobacter细菌病例.
- 为了将这些病例与之前发表的Campylobacter bacteremia报告进行比较.
- 在特定的患者群体中调查坎皮洛巴克特细菌病的临床特征和结果.
主要方法:
- 对12例Campylobacter bacteremia病例进行了回顾性分析.
- 在实施新的血液培养基后检测病例.
- 对患者的症状,潜在疾病和实验室数据的审查,包括血液和液培养物.
- 使用Child-Pugh和末期肝病模型 (MELD) 评分来评估疾病严重程度.
主要成果:
- 发烧 (67%),腹痛 (50%) 和吐 (33%) 是最常见的症状;腹仅在17%的病例中出现.
- 慢性肝病是重要的潜在疾病,影响了75%的患者.
- 坎比洛巴克特 (Campylobacter jejuni) 是被分离的主要物种 (50%).
- 住院死亡率为8%,归因于二次性大肠杆菌败血症.
结论:
- 在这个印度队伍中,坎皮洛巴克特菌病的出现异常,腹发病率较低.
- 慢性肝病是侵入性坎皮洛巴克特菌感染的主要危险因素.
- 改进的检测方法,如新的血液培养基,可以提高识别罕见的细菌感染,如Campylobacter bacteremia.
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