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Updated: Jun 15, 2025

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通过将血,脑液和大脑的pQTL与GWAS总结数据集成来识别双相情感障碍的新型蛋白质

Zhehao Xiao1,2, Nan Zheng1,3, Haodong Chen1,2

  • 1Fujian Medical University Union Hospital, Fuzhou, China.

Translational psychiatry
|August 27, 2024
PubMed
概括

这项研究使用遗传数据发现与双相情感障碍 (BD) 风险相关的蛋白质. 较高的CSF AGRP,FRZB和IL36A增加了BD风险,而较低的CSF CTSF,LRP8和等离子FLRT3降低了风险.

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Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
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