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对于最大IL-2信号传递和T细胞增殖,STAT5A和STAT5B的氨酸酸化是必要的

Jian-Xin Lin1, Meili Ge2,3, Cheng-Yu Liu4

  • 1Laboratory of Molecular Immunology and Immunology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, 20892-1674, USA. linjx@nhlbi.nih.gov.

Nature communications
|August 27, 2024
PubMed
概括

STAT5A和STAT5B的氨酸酸化对于CD8+T细胞发育和IL-2信号传递至关重要. 这项研究揭示了它在T细胞增殖和活体功能中的关键作用.

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