相关实验视频

Updated: Jun 15, 2025

Optimization of In vitro Transcription Reaction for mRNA Production Using Chromatographic At-Line Monitoring
07:04

Optimization of In vitro Transcription Reaction for mRNA Production Using Chromatographic At-Line Monitoring

Published on: April 4, 2025

279

优化mRNA疫苗的5'未翻译区域

Qi Ma1, Xiaoguang Zhang1, Jing Yang1

  • 1National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Yingxin Street #100, Xicheng District, Beijing, 100052, China.

Scientific reports
|August 27, 2024
PubMed
概括

该研究发现,β-环球蛋白5'未翻译区域 (UTR) 显著提高mRNA疫苗的翻译效率. 这一发现支持在未来的mRNA疫苗开发中使用β-环球蛋白5'UTR.

关键词:
艾滋病毒疫苗 艾滋病毒疫苗在体外转录 In vitro转录记者基因表达系统未翻译的地区.在mRNA疫苗的使用中.

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