肠癌后健康饮食和积极的生活方式 (HEAL ABC) - 可行性随机对照试验
Jana Sremanakova1, Anne Marie Sowerbutts2, Chris Todd2,3,4,5
1School of Health Sciences, University of Manchester, Oxford Road, Manchester, M13 9PL, UK. jana.sremanakova@manchester.ac.uk.
European journal of clinical nutrition
|August 27, 2024
概括
对结直肠癌幸存者的生活方式干预是可行的,具有高的保留率和参与者满意度. 干预改善了饮食质量,减少了超加工食品的摄入量,但注意到招聘挑战.
科学领域:
- 在瘤学瘤学.
- 生活方式 医学 医疗
- 公共卫生 公共卫生
背景情况:
- 健康的生活方式与改善癌症存活率有关,但随机对照试验 (RCT) 证据有限.
- 这项研究解决了对生活方式干预后结肠直肠癌 (CRC) 治疗的可行性数据的需求.
研究的目的:
- 测试生活方式干预对结直肠癌幸存者的可行性.
- 评估参与者的坚持,保留和干预的可接受性.
- 探索对饮食质量和超加工食品消费的初步影响.
主要方法:
- 采用了一种混合方法的随机对照试验 (RCT).
- 参与者接受了为期3个月的基于世界癌症研究基金/美国癌症研究所 (WCRF/AICR) 建议,健康行动过程方法和动机面试或标准护理的基于电话的生活方式干预.
- 在六个月的随访期间评估了可行性,保留和次要结果.
主要成果:
- 招聘证明具有挑战性,招聘率为48.6%.
- 实现了高干预完成率 (97%) 和随访率 (89%).
- 参与者报告说,干预措施是可以接受的,满足了他们的需求,并促进了问责制. 观察到WCRF/AICR得分显著改善,超加工食品摄入量减少10%.
结论:
- 在87%的结直肠癌幸存者中,HEAL ABC生活方式干预证明了可行性.
- 干预支持健康生活方式的改变,并显示对饮食质量产生积极影响.
- 替代性招聘策略对于未来充足的RCT来说至关重要,以确认干预的有效性.
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